Decontamination with vaporized hydrogen peroxide is effective against Mycobacterium tuberculosis
Decontamination with vaporized hydrogen peroxide is effective against Mycobacterium tuberculosis
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DOI：
10.1111/j.1472-765x.2005.01683.x
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发表时间：
2005-06-01
影响因子：
2.4
通讯作者：
Kaufmann, S. H. E.
中科院分区：
文献类型：
--
作者：
Kahnert, A.;Seiler, P.;Kaufmann, S. H. E.
目的：目的：探讨汽化过氧化氢（VHP）室内熏蒸消毒对活结核分枝杆菌的消毒效果。结核H37Rv和M.结核病北京在10 μ l滴在组织培养板中干燥，放置在蒸汽可渗透的Tyvek袋中，并分布在实验室表面上。房间暴露于空调提供的VHP。测试了不同的暴露条件。结论：VHP处理是减少和消除M.本研究的意义和影响：VHP熏蒸是甲醛熏蒸的一种替代方法，特别是在结核病研究实验室的动物房净化方面。
Aims: To determine the efficacy of room fumigation with vaporized hydrogen peroxide (VHP) in decontamination of viable Mycobacterium tuberculosis.Methods and Results: About 8 x 10(4)-2.3 x 10(6) CFU of M. tuberculosis H37Rv and M. tuberculosis Beijing were dried in 10-mu l drops in tissue culture plates, placed in steam-permeable Tyvek pouches and distributed on laboratory surfaces. The room was exposed to VHP delivered by air conditioning. Different exposure conditions were tested. Exposure to VHP resulted in sterilization of the bacterial samples in three different test runs.Conclusions: VHP treatment is an effective means of reducing and eliminating room contaminations of M. tuberculosis.Significance and Impact of the Study: Fumigation with VHP represents an alternative to formaldehyde fumigation, particularly for decontamination of animal rooms in tuberculosis research laboratories.