CONJUGATIVE TRANSFER BY THE VIRULENCE SYSTEM OF AGROBACTERIUM-TUMEFACIENS
CONJUGATIVE TRANSFER BY THE VIRULENCE SYSTEM OF AGROBACTERIUM-TUMEFACIENS
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DOI：
10.1126/science.256.5061.1324
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发表时间：
1992-05-29
期刊：
影响因子：
56.9
通讯作者：
HOOYKAAS, PJJ
中科院分区：
文献类型：
--
作者：
BEIJERSBERGEN, A;DENDULKRAS, A;HOOYKAAS, PJJ
在诱导肿瘤的过程中，根癌农杆菌将其钛质粒(T-DNA)的一部分转移到植物细胞。这种T-DNA在植物细胞中的表达导致它们转化为肿瘤细胞。T-DNA转移到植物体内的过程与细菌接合的过程有相似之处。在这里，T-DNA转移机制介导了细菌之间的接合。因此，通常参与DNA从细菌到植物转移的根癌农杆菌Ti质粒Vir区的产物可以指导INQ质粒在农杆菌之间的接合转移。
Agrobacterium tumefaciens transfers part of its Ti plasmid, the transferred DNA (T-DNA), to plant cells during tumor induction. Expression of this T-DNA in plant cells results in their transformation into tumor cells. There are similarities between the process of T-DNA transfer to plants and the process of bacterial conjugation. Here, the T-DNA transfer machinery mediated conjugation between bacteria. Thus, products of the Vir region of the Ti plasmid of Agrobacterium tumefaciens, normally involved in transfer of DNA from bacteria to plants, can direct the conjugative transfer of an IncQ plasmid between agrobacteria.