Detection of fasciculations in amyotrophic lateral sclerosis: The optimal ultrasound scan time
Detection of fasciculations in amyotrophic lateral sclerosis: The optimal ultrasound scan time
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DOI：
10.1002/mus.25607
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发表时间：
2017-12-01
期刊：
影响因子：
3.4
通讯作者：
Kiernan, Matthew C.
中科院分区：
文献类型：
--
作者：
Noto, Yu-ichi;Shibuya, Kazumoto;Kiernan, Matthew C.
本研究旨在探讨超声检测肌萎缩侧索硬化症(ALS)的最佳扫描时间。方法记录ALS患者舌部、腹部和四肢肌肉肌束的间隔时间，并结合发生2个肌束的累积概率进行评估。结果在对19例ALS患者228块肌肉进行前瞻性研究后，68%的患者能发现肌束。记录到的手部肌束间最长间期为81.4%S。所有肌肉在60秒内出现2次束征的累积概率为0.9。讨论在60 S扫描时间内出现2次或2次以上束征的定义可以可靠地检测出肌萎缩侧索硬化症。肌肉神经，2017
IntroductionThis study seeks to elucidate the optimal scan time to detect fasciculations by using ultrasound in the diagnosis of amyotrophic lateral sclerosis (ALS).MethodsThe intervals between fasciculations were recorded from tongue, abdominal, and limb muscles in ALS patients, incorporating assessment of the cumulative probability of 2 fasciculations occurring.ResultsFrom prospective studies of 228 muscles from 19 ALS patients, fasciculations were detectable in 68% of patients. The longest interfasciculation interval recorded was 81.4 s in the hand muscle. The cumulative probability of 2 fasciculations occurring was calculated as 0.9 in all muscles during a period of 60 s.DiscussionA definition of 2 or more fasciculations occurring during a scan time of 60 s reliably allowed detection of fasciculations in ALS. Muscle Nerve, 2017