Patterns of Adherence to Oral Hypoglycemic Agents and Glucose Control among Primary Care Patients with Type 2 Diabetes.
Patterns of Adherence to Oral Hypoglycemic Agents and Glucose Control among Primary Care Patients with Type 2 Diabetes.
复制标题
2 型糖尿病初级保健患者口服降糖药的依从性和血糖控制模式。
DOI：
10.1080/08964289.2014.904767
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Bogner,HillaryR
中科院分区：
文献类型：
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作者：
deVriesMcClintock,HeatherF;Morales,KnashawnH;Small,DylanS;Bogner,HillaryR
研究人员试图检查2型糖尿病初级保健患者是否存在与患者特征和临床结局相关的口服降糖药依从性模式。通过生长曲线混合模型进行纵向分析，根据12周内口服降糖药的依从性模式对180例参与依从性干预的患者进行分类。确定了三种依从性变化模式：依从性、增加依从性和非依从性。总体认知和干预条件与依从性变化模式相关（p<0.05）。与非依从性模式患者相比，依从性模式增加的患者更有可能在12周时血红蛋白A1 c（HbA 1c）< 7%;校正比值比= 14.52，95% CI（2.54，82.99）。识别有不依从风险的2型糖尿病患者对于临床预后以及干预措施的制定和实施非常重要。
Researchers sought to examine whether there are patterns of oral hypoglycemic-agent adherence among primary-care patients with type 2 diabetes that are related to patient characteristics and clinical outcomes. Longitudinal analysis via growth curve mixture modeling was carried out to classify 180 patients who participated in an adherence intervention according to patterns of adherence to oral hypoglycemic agents across 12 weeks. Three patterns of change in adherence were identified: adherent, increasing adherence, and nonadherent. Global cognition and intervention condition were associated with pattern of change in adherence (p< .05). Patients with an increasing adherence pattern were more likely to have an Hemoglobin A1c(HbA1c) < 7%; adjusted odds ratio = 14.52, 95% CI (2.54, 82.99) at 12 weeks, in comparison with patients with the nonadherent pattern. Identification of patients with type 2 diabetes at risk of nonadherence is important for clinical prognosis and the development and delivery of interventions.