Difference in prevalence of metabolic syndrome between Japanese outpatients and inpatients with schizophrenia: A nationwide survey
Difference in prevalence of metabolic syndrome between Japanese outpatients and inpatients with schizophrenia: A nationwide survey
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日本精神分裂症门诊患者和住院患者代谢综合征患病率的差异：一项全国性调查
DOI：
10.1016/j.schres.2016.01.016
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发表时间：
2016
影响因子：
4.5
通讯作者：
Someya T
中科院分区：
文献类型：
--
作者：
Sugai T;Suzuki Y;Yamazaki M;Shimoda K;Mori T;Ozeki Y;Matsuda H;Sugawara N;Yasui-Furukori N;Minami Y;Okamoto K;Sagae T;Someya T
精神分裂症患者患代谢综合征（MetS）的风险较高。MetS患病率因种族而异。虽然环境因素，如缺乏体力活动和不平衡的饮食，可以导致代谢综合征，这些可能是不同的门诊和住院精神分裂症患者。日本的精神卫生保健制度与其他国家不同。然而，很少有研究调查MetS在日本精神分裂症患者中的患病率。因此，我们在全国范围内进行了一项调查，以明确日本精神分裂症门诊和住院患者中MetS的患病率。我们通过问卷调查了520家门诊机构和247家住院机构的MetS风险。门诊7655人，住院15,461人。MetS患病率基于国家胆固醇教育计划成人治疗组III使用ATP III-A定义的门诊患者的总体MetS患病率为34.2%，男性为37.8%，女性为29.4%，而住院患者为13.0%，男性为12.3%，女性为13.9%。门诊患者的MetS患病率约为住院患者的2- 3倍。总之，日本门诊患者的MetS患病率约为住院患者的3倍。因此，考虑到门诊和住院患者的健康特征差异，我们应该更加关注日本精神分裂症患者的躯体疾病风险。
Patients with schizophrenia have a higher risk of metabolic syndrome (MetS). MetS prevalence varies with ethnicity. Although environmental factors, such as lack of physical activity and unbalanced diet, can lead to MetS, these may differ between outpatients and inpatients with schizophrenia. The Japanese mental health care system differs from that in other countries. However, few studies have investigated the prevalence of MetS in Japanese patients with schizophrenia. Therefore, we conducted a nationwide survey to clarify the prevalence of MetS in Japanese outpatients and inpatients with schizophrenia.We investigated the risk of MetS by questionnaire in 520 facilities for outpatients and 247 facilities for inpatients. There were 7655 outpatients and 15,461 inpatients with schizophrenia. MetS prevalence was based on the National Cholesterol Education Program Adult Treatment Panel III (ATP III-A) and the Japan Society for the Study of Obesity (JASSO).The overall MetS prevalence in outpatients using the ATP III-A definition was 34.2%, with 37.8% in men and 29.4% in women, compared with 13.0% in inpatients, with 12.3% in men and 13.9% in women. MetS prevalence in outpatients was approximately 2- to 3-fold higher than in inpatients.In conclusion, MetS prevalence in Japanese outpatients was approximately 3-fold higher than in inpatients. Therefore, we should pay more attention to the risk of physical disease in Japanese patients with schizophrenia, considering the difference in health characteristics between outpatients and inpatients.