Electrostatically Driven Topological Freezing of Polymer Diffusion at Intermediate Confinements
Electrostatically Driven Topological Freezing of Polymer Diffusion at Intermediate Confinements
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DOI：
10.1103/physrevlett.126.057802
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发表时间：
2021-02-03
影响因子：
8.6
通讯作者：
Muthukumar, Murugappan
中科院分区：
文献类型：
--
作者：
Jia, Di;Muthukumar, Murugappan
打破了聚合物在拥挤的水介质中遵循爱因斯坦扩散定律的范式，我们报道了在中间约束下的局域非扩散分层亚稳态。结合静电和拓扑效应，我们可以在由相反电荷的主体水凝胶中的客体多氨基酸链组成的准醋酸凝胶体系中调节这一新的普适性类别的倾向。我们的观察结果为控制大分子在水基拥挤介质中的释放和保留提供了策略，同时为理解聚合物和其他软物质系统中的拓扑受阻动力学开辟了新的方向。
Breaking the paradigm that polymers in crowded aqueous media obey Einstein's law of diffusion, we report a localized nondiffusive hierarchical metastable state at intermediate confinements. Combining electrostatic and topological effects, we can tune the propensity of this new universality class in a quasicoacervate gel system consisting of guest polyamino acid chains inside an oppositely charged host hydrogel. Our observations offer strategies for controlled release and retention of macromolecules in aqueous crowded media, while opening a new direction for understanding topologically frustrated dynamics in polymers and other soft matter systems.