Intensity of exposure and incidence of melioidosis in Thai children.
Intensity of exposure and incidence of melioidosis in Thai children.
复制标题
DOI：
10.1016/s0035-9203(08)70010-5
复制
发表时间：
2008-12-01
影响因子：
2.2
通讯作者：
Peacock, Sharon J
中科院分区：
文献类型：
--
作者：
Cheng, Allen C;Wuthiekanun, Vanaporn;Peacock, Sharon J
在泰国，类鼻疽伯克霍尔德菌抗体的背景血清阳性率较高，限制了其作为诊断工具的使用。据信，这是由于儿童暴露于泥浆和地表水中的细菌造成的。随着年龄的增长，抗体的流行率越来越高，这是暴露强度的标志。用儿童血清阳性率数据校准了易感-感染-易感（SIS）模型（
There is a high background seroprevalence of antibodies to Burkholderia pseudomallei in Thailand that limits its use as a diagnostic tool. It is believed that this results from childhood exposure to the bacterium in mud and surface water. The increasing prevalence of antibodies with age is a marker of the intensity of exposure. A susceptible-infected-susceptible (SIS) model was calibrated with data on seroprevalence in children (