Reenvisioning Clinical Science: Unifying the Discipline to Improve the Public Health.
Reenvisioning Clinical Science: Unifying the Discipline to Improve the Public Health.
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DOI：
10.1177/2167702613497932
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发表时间：
2014-01-01
期刊：
影响因子：
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通讯作者：
Riddle M
中科院分区：
文献类型：
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作者：
Onken LS;Carroll KM;Shoham V;Cuthbert BN;Riddle M
我们提出了一个愿景的临床科学，干预发展的概念框架的基础上，由特拉华州项目。该框架基于更新的阶段模型，将机制的基础科学问题纳入临床科学研究的每个阶段。提出的愿景旨在统一临床科学的各个方面，以实现开发最有效和可实施的干预措施的共同目标，同时揭示新的科学途径，其中基本目标和应用目标同样重要。在这种综合的，转化模型的培训可以帮助学生学习如何进行临床科学的每个领域的研究，并在干预发展的每个阶段。这一愿景旨在推动该领域实现产生可实施和有效的治疗和预防干预措施的公共卫生目标。
We present a vision of clinical science, based on a conceptual framework of intervention development endorsed by the Delaware Project. This framework is grounded in an updated stage model that incorporates basic science questions of mechanisms into every stage of clinical science research. The vision presented is intended to unify various aspects of clinical science toward the common goal of developing maximally potent and implementable interventions, while unveiling new avenues of science in which basic and applied goals are of equally high importance. Training in this integrated, translational model may help students learn how to conduct research in every domain of clinical science and at each stage of intervention development. This vision aims to propel the field to fulfill the public health goal of producing implementable and effective treatment and prevention interventions.