Programmed Assembly of Host-Guest Protein Crystals

Programmed Assembly of Host-Guest Protein Crystals
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DOI:
10.1002/smll.201602703
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发表时间:
2017-02-17
期刊:
影响因子:
13.3
通讯作者:
Snow, Christopher D.
Snow, Christopher D.
中科院分区:
材料科学1区
文献类型:
--
作者:
Huber, Thaddaus R.;Hartje, Luke F.;Snow, Christopher D.

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在具有13 nm轴向孔的蛋白质晶体中,客体荧光蛋白的结合和释放受到控制。空间分离的客体蛋白装载通过顺序结合和释放阶段实现。此外,晶体外部的选择性稳定导致空心结晶壳。
The binding and release of guest fluorescent proteins inside a protein crystal with 13 nm axial pores is controlled. Spatially segregated guest protein loading is achieved via sequential binding and release stages. Additionally, selective stabilization of the crystal exterior results in hollow crystalline shells.