VASOPRESSIN AND NORADRENALINE COEXISTENCE IN THE RAT LOCUS CERULEUS - DIFFERENTIAL DECREASES OF THEIR LEVELS IN DISTANT BRAIN-AREAS AFTER THERMAL AND NEUROTOXIC LESIONS
VASOPRESSIN AND NORADRENALINE COEXISTENCE IN THE RAT LOCUS CERULEUS - DIFFERENTIAL DECREASES OF THEIR LEVELS IN DISTANT BRAIN-AREAS AFTER THERMAL AND NEUROTOXIC LESIONS
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DOI：
10.1016/0006-8993(88)90657-9
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发表时间：
1988-09-06
期刊：
影响因子：
2.9
通讯作者：
VANDERGUGTEN, J
中科院分区：
文献类型：
--
作者：
CAFFE, AR;VANLEEUWEN, FW;VANDERGUGTEN, J
加压素（VP）和去甲肾上腺素（NA）共存于大鼠蓝斑（LC）。热损伤后的LC，但是，没有检测到的损失VP免疫反应纤维在大脑中进行了检查。在单侧LC损伤后，还测量了皮质、海马和小脑中的VP和NA水平。只有同侧NA水平的显着耗尽被发现。因此，没有迹象表明VP运输LC神经元向远处的脑区。
Vasopressin (VP) and noradrenaline (NA) coexist in the rat locus ceruleus (LC). After thermal lesions of the LC, however, no detectable loss of VP-immunoreactive fibers was examined in the brain. VP and NA levels were also measured in the cortex, hippocampus and cerebellum, after unilateral LC lesions. Only significant ipsilateral depletions of NA levels were found. Therefore, no indications were obtained for VP transport by LC neurons towards distant brain areas.