Effects of compound Rohoodiola on immunity,anti-hypoxia and anti-tiredness in mice
Effects of compound Rohoodiola on immunity,anti-hypoxia and anti-tiredness in mice
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发表时间：
2008
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通讯作者：
H. Ying
中科院分区：
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作者：
H. Ying
目的探讨复方红景天对小鼠免疫、抗缺氧、抗疲劳的作用。方法将6周龄健康昆明小鼠随机分为0.9%NS对照组、西洋参对照组、复方红景天汤低剂量组和高剂量组。检测杆试验、负重游泳试验、常压耐缺氧、碳清除能力试验（吞噬指数）、免疫器官重量（脾脏指数、胸腺指数）。结果复方Rohoodiola可显着延长小鼠持续负重游泳和攀爬时间，HR组与NS组差异显着（P<0。01），但不能延长小鼠抗缺氧时间，与NS相比，还能增强小鼠清除能力。指数,提高脾指数和胸腺指数(P<0。05)。结论复方红景天对增强小鼠抗疲劳能力、改善小鼠免疫功能有明显作用。
Objective To investigate the effects of compound Rohoodiola on immunity,anti-hypoxia and anti-tiredness in mice.Methods Healthy Kunming mice aged 6 weeks were randomly divided into 0.9% NS control group,Panax Quinquefolium control group,Rohodiola herb compound decoction low dosage group and high dosage group.In order to observe the effects of compound Rohoodiola on a nti-tiredness and immunity after treatment and adaptive training for 4 weeks,the indexes of the pole test,loading swimming test,bearing hypoxia at normal pressure,carbon clearance capacity test(phagocytic index),and immune organs weight(spleen index and the thymus index) were detected.Results The compound Rohoodiola could elongate the continual loading swimming and climbing time markedly,and the difference between HR group and NS group was significant(P0.01).But it couldn't prolong anti-hypoxia time of mice.Compared with N.S,it also enhanced mouse clearance capacity index,improved the spleen index and the thymus index(P0.05).Conclusion The compound Rohodiola has obvious effects to enhance the mouse abilities on anti-tiredness and improve the mouse immune function.