CRITERIA FOR SCREENING-TESTS FOR GESTATIONAL DIABETES
CRITERIA FOR SCREENING-TESTS FOR GESTATIONAL DIABETES
复制标题
DOI：
10.1016/0002-9378(82)90349-0
复制
发表时间：
1982-01-01
影响因子：
9.8
通讯作者：
COUSTAN, DR
中科院分区：
文献类型：
--
作者：
CARPENTER, MW;COUSTAN, DR
对381名25岁或25岁以上的孕妇进行了50g的1小时葡萄糖筛查试验。所有有血糖值的女性。对130 mg/dl(119 mg/dl，全血)受试者进行100g 3h糖耐量试验，按O‘Sullivan’S诊断标准诊断妊娠期糖耐量异常。根据筛查测试值的分布，可以识别出3个诊断区：血糖低于135 mg/dl的区域，患糖尿病的概率低于1%；血糖高于182 mg/dl的区域，糖尿病的可能性超过95%；以及中心不确定区(135~182 mg/dl，血糖)，需要进一步检测。显然，进一步检测的阈值应该从143 mg/dl降至135 mg/dl。
A 50 g, 1-h glucose screening test was given to 381 gravid women 25 yr of age or older. All women with plasma glucose values .gtoreq. 130 mg/dl (119 mg/dl, whole blood) were given a 100 g, 3-h glucose tolerance test to diagnose gestational glucose intolerance using O''Sullivan''s diagnostic criteria. On the basis of the distribution of screening test values, 3 diagnostic zones could be identified: a zone below 135 mg/dl plasma glucose, with less than 1% probability of diabetes; a zone above 182 mg/dl plasma glucose, with more than 95% probability of diabetes; and a central zone of uncertainty (135 to 182 mg/dl, plasma glucose), where further testing is required. Apparently thresholds for further testing should be lowered from 143 to 135 mg/dl of plasma glucose.