Inflammatory and immune effects on tumor progression.
Inflammatory and immune effects on tumor progression.
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DOI：
10.1016/j.it.2021.11.009
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发表时间：
2021-12
影响因子：
16.8
通讯作者：
Kamiya Mehla;M. Hollingsworth
中科院分区：
文献类型：
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作者：
Kamiya Mehla;M. Hollingsworth
已知肿瘤进展发生在导致遗传、细胞和代谢适应的复杂微环境中。Martinet等和Del Poggettoet等的两篇文章启发了我们炎症和免疫系统在引导癌前细胞向致癌转化的进展以及随后的肿瘤演变中的作用。
Tumor progression is known occur in a complex microenvironment that leads to genetic, cellular, and metabolic adaptations. Two articles from Martinet al. and Del Poggettoet al. enlighten us on the role of inflammation and the immune system in guiding the progression of preneoplastic cells to oncogenic transformation and on subsequent tumor evolution.