Scanning Probe Microscopy of Nanocomposite Membranes and Dynamic Organization
Scanning Probe Microscopy of Nanocomposite Membranes and Dynamic Organization
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DOI：
10.1002/adfm.201203429
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发表时间：
2013-05-28
影响因子：
19
通讯作者：
Goodwin, Peter M.
中科院分区：
文献类型：
--
作者：
Montano, Gabriel A.;Adams, Peter G.;Goodwin, Peter M.
纳米复合膜组件是一类包含无机/有机纳米级材料的材料，如富勒烯和金纳米颗粒，或具有生物启发的两亲性结构的纳米结构材料，由分子（如脂质或嵌段共聚物）组成。这种材料的一个有趣之处在于，它具有开发可编程膜组件的潜力，可以模拟生物膜的复杂性、动力学和功能。由于组件的纳米级性质，有必要以纳米级分辨率了解这些材料之间的相互作用。尽管许多技术能够提供关于膜基组件整体组织的信息，但只有扫描探针显微镜（SPM）方法允许在环境相关条件下直接可视化随机过程。在这里，概述了纳米复合膜和薄膜结构的研究，重点是使用原位原子力显微镜（AFM）结合荧光显微镜/光谱学技术来理解组织和动力学，以及与集成纳米技术中心的活动和能力有关的研究。
Nanocomposite membrane assemblies are a class of materials that incorporate inorganic/organic nanoscale materials, such as fullerenes and gold nanoparticles or nanostructured materials with bio-inspired amphiphilic structures composed of molecules such as lipids or block copolymers. One of the intrigues of such materials is the potential to develop programmable membrane assemblies that mimic biological membrane complexity, dynamics and function. Due to the nanoscale nature of the assemblies, it becomes necessary to understand interactions between these materials with nanoscale resolution. Although many techniques are able to provide information as to the overall organization of membrane-based assemblies, only scanning probe microscopy (SPM) methods allow for a direct visualization of stochastic processes under environmentally relevant conditions. Here, an overview of nanocomposite membrane and thin film architecture investigations is presented with an emphasis on using in situ atomic force microscopy (AFM) in combination with fluorescence microscopy/spectroscopy techniques to understand organization and dynamics, in relation to activities and capabilities at the Center for Integrated Nanotechnologies.