Hypothalamic-pituitary-gonadal axis and cortisol in young women with primary fibromyalgia: the potential roles of depression, fatigue, and sleep disturbance in the occurrence of hypocortisolism

Hypothalamic-pituitary-gonadal axis and cortisol in young women with primary fibromyalgia: the potential roles of depression, fatigue, and sleep disturbance in the occurrence of hypocortisolism
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DOI:
10.1136/ard.2003.014969
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发表时间:
2004-11-01
影响因子:
27.4
通讯作者:
Em, S
Em, S
中科院分区:
医学1区
文献类型:
--
作者:
Gur, A;Cevik, R;Em, S

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Objectives: To investigate abnormalities of the hypothalamic-pituitary-gonadal (HPG) axis and cortisol concentrations in young women with primary fibromyalgia ( FM); and to determine whether depression, fatigue, and sleep disturbance affect these hormones.Methods: Follicle stimulating hormone (FSH), luteinising hormone (LH), oestradiol, progesterone, prolactin, and cortisol concentrations in 63 women with FM were compared with those in 38 matched healthy controls; all subjects aged