Adherence of pediatric patients to automated peritoneal dialysis

Adherence of pediatric patients to automated peritoneal dialysis
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DOI:
10.1007/s00467-011-1792-2
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发表时间:
2011-05-01
影响因子:
3
通讯作者:
Warady, Bradley A.
Warady, Bradley A.
中科院分区:
医学3区
文献类型:
--
作者:
Chua, Annabelle N.;Warady, Bradley A.

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关于终末期肾病儿童家庭自动腹膜透析(APD)处方依从性的信息很少。因此,我们回顾性地回顾了接受家庭APD治疗的< 21岁患者的HomeChoice PRO Card数据。通过将四个测量的处方变量(疗程/月、每次疗程持续时间、周期数/次、透析液量/次)中的每一个的频率除以规定的频率并乘以100,依从性的特征是发生在千分之95%、90-94%或< 90%的时间内。分别评估了治疗依从性与患者年龄、性别、种族以及患者是否接受过培训之间的关系。在51例患者(57%为男性)中,腹膜透析(PD)发病的平均年龄为11.8±5.3岁,28例(55%)在所有变量中都是坚持的。两组患者的平均年龄和是否接受过训练没有差异。与非裔美国人(p = 0.048)相比,男性更有可能成为非信徒(p = 0.026)。大多数患者坚持疗程(96%)和周期数(92%),而不坚持更常见的是疗程数(82%)和透析量(78%)。总之,在我们的研究队列中,45%的儿童患者表现出一定程度的不遵守APD处方方案,这强调了密切监测儿童家庭透析效果的价值。
Little information is available on adherence to a home automated peritoneal dialysis (APD) prescription for children with end-stage renal disease. We have therefore retrospectively reviewed HomeChoice PRO Card data from patients < 21 years of age who received home APD. Adherence was characterized as occurring a parts per thousand yen95%, 90-94%, or < 90% of time by dividing the frequency of each of four measured prescription variables (sessions/month, duration of each session, number of cycles/session, volume of dialysate/session) by the prescribed frequency and multiplying by 100. The relationship between treatment adherence and patient age, gender, race and if the patient had received training, respectively, was assessed. Of the 51 patients (57% male), with a mean age at peritoneal dialysis (PD) onset of 11.8 +/- 5.3 years, 28 (55%) were adherent for all variables. No difference in mean age or if patients were trained existed between the two groups. Males were more likely to be non-adherent (p = 0.026) as were African Americans (p = 0.048). The majority of patients were adherent to duration (96%) and number of cycles (92%), whereas non-adherence was more common with number of sessions (82%) and dialysate volume (78%). In conclusion, 45% of the pediatric patients in our study cohort exhibited some non-adherence to their prescribed APD regimen, emphasizing the value of closely monitoring the performance of home dialysis in children.