Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers.
Preliminary assessment of nasopharyngeal carcinoma incidence in the Philippines: a second look at published data from four centers.
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DOI：
10.5732/cjc.013.10010
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发表时间：
2014-03
影响因子：
--
通讯作者：
Mejia MB
中科院分区：
文献类型：
--
作者：
Sarmiento MP;Mejia MB
在中国南部和东南亚等流行地区，鼻咽癌（NPC）的年发病率为每10万人3至30人。在菲律宾，2010年的估计发病率为每10万人1.2例。然而，这一比率是基于从该国仅两个地区的登记处收集的数据。在这里，我们报告了我们的研究结果，以更好地估计菲律宾NPC的发病率。在2011年9月1日至2012年8月31日期间，使用NPC筛查问卷收集了来自4个不同机构（圣托马斯大学、马卡蒂医疗中心、菲律宾肿瘤中心公司和红衣主教桑托斯纪念医疗中心）的49名患者的数据。粗发病率为0.09 / 10万。使用Segi和WHO标准的年龄标准化发病率分别为2.08 / 10万和1.79 / 10万。49例患者中，男性31例，女性18例，年龄在30 ~ 59岁之间的占71%。世卫组织II型和III型分别占22%和78%，75.5%的病例为局部晚期（III - ivb期）。虽然4所机构的年龄标准化发病率在数值上高于已发表的年龄标准化发病率（2.07 / 10万比1.2 / 10万），但双比例z检验显示两者之间无显著差异（P = 0.68）。为了更好地估算全国人大的疾病负担，需要作出更加协调一致的努力。
In endemic regions such as southern China and Southeast Asia, the annual incidence of nasopharyngeal carcinoma (NPC) ranges from 3 to 30 per 100,000. In the Philippines, the estimated incidence in 2010 was 1.2 per 100,000. However, this rate is based on data collected from registries covering only two regions in the country. Here, we report the findings from our study to better approximate the incidence of NPC in the Philippines. Between September 1, 2011 and August 31, 2012, data were collected from 49 patients from 4 different institutions—University of Santo Tomas, Makati Medical Center, Philippine Oncology Center Corporation, and Cardinal Santos Memorial Medical Center—using a NPC screening questionnaire. Crude incidence was 0.09 per 100,000. Age-standardized incidences using Segi and WHO standards were 2.08 and 1.79 per 100,000, respectively. Of the 49 patients, 31 were males and 18 were females, and 71% of patients were between 30 and 59 years old. WHO types II and III represented 22% and 78% of the subjects, respectively, and 75.5% of cases were locally advanced (stages III–IVB). Although the age-standardized incidence from the 4 institutions was numerically higher than the published age-standardized incidence (2.07 per 100,000 vs. 1.2 per 100,000), two-proportion z-test showed no significant difference between them (P = 0.68). A more concerted effort is needed for a better approximation of the country's NPC disease burden.
影响因子：
2.4
作者：
Ngelangel, CA;Wang, EHM
通讯作者：
Wang, EHM