Healthy ageing trajectories and lifestyle behaviour: the Mexican Health and Aging Study
Healthy ageing trajectories and lifestyle behaviour: the Mexican Health and Aging Study
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DOI：
10.1038/s41598-019-47238-w
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发表时间：
2019-07-30
影响因子：
4.6
通讯作者：
Prina, Matthew
中科院分区：
文献类型：
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作者：
Daskalopoulou, Christina;Koukounari, Artemis;Prina, Matthew
预测显示，到2050年，墨西哥60岁以上的人口数量将增加两倍。然而，老龄化的特点是健康状况变化很大。在这项研究中，我们的目标是在一项具有代表性的墨西哥老年人队列研究中确定健康轨迹及其与生活方式因素的关联。我们使用了来自墨西哥健康和老龄化研究(MHAS)的14,143名成年人的次要数据。基于功能能力概念框架的健康测量被映射到四个波(2001、2003、2012、2015)，并应用贝叶斯多水平项目反应理论(IRT)建立。条件生长混合模型(GMM)被用来识别具有相似轨迹的潜在类别的个体，并检查体育活动、吸烟和酒精对这些个体的影响。根据社会人口学和生活方式行为的条件，提出了四个潜在类别：高稳定、中等稳定、低稳定和下降。没有从事体力活动、现吸烟者或以前吸烟者以及未在基线水平饮酒的参与者更有可能处于恶化程度最高的轨迹(即下降者)。这项研究证实了年龄的异质性和健康生活方式的积极影响。这些结果为制定新政策奠定了基础。
Projections show that the number of people above 60 years old will triple by 2050 in Mexico. Nevertheless, ageing is characterised by great variability in the health status. In this study, we aimed to identify trajectories of health and their associations with lifestyle factors in a national representative cohort study of older Mexicans. We used secondary data of 14,143 adults from the Mexican Health and Aging Study (MHAS). A metric of health, based on the conceptual framework of functional ability, was mapped onto four waves (2001, 2003, 2012, 2015) and created by applying Bayesian multilevel Item Response Theory (IRT). Conditional Growth Mixture Modelling (GMM) was used to identify latent classes of individuals with similar trajectories and examine the impact of physical activity, smoking and alcohol on those. Conditional on sociodemographic and lifestyle behaviour four latent classes were suggested: high-stable, moderate-stable, low-stable and decliners. Participants who did not engage in physical activity, were current or previous smokers and did not consume alcohol at baseline were more likely to be in the trajectory with the highest deterioration (i.e. decliners). This study confirms ageing heterogeneity and the positive influence of a healthy lifestyle. These results provide the ground for new policies.