A Coding Scheme for Nucleic Acid Memory (NAM).
A Coding Scheme for Nucleic Acid Memory (NAM).
复制标题
核酸记忆（NAM）的编码方案。
DOI：
10.1109/wmed.2017.7916922
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Andersen,Tim
中科院分区：
文献类型：
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作者：
Suyehira,Kelsey;Llewellyn,Simon;Zadegan,RezaM;Hughes,WilliamL;Andersen,Tim
预计到2040年，全球对数字数据的需求将超过半导体级硅的供应[1]。当结合需要存档信息[2]时，核酸正在被探索作为替代记忆材料[1-7]。根据最近的一项研究，核酸存储器（NAM）的信息密度比闪存大一千倍，并具有持续数百年的能力[1]。这里介绍的是一种算法，用于将数字数据转换为用于冰川存储的独特DNA序列。受生物学启发，我们的编码方案将十六进制字符映射到三个DNA核苷酸的序列。这种映射避免了可能具有不利影响的重复序列和起始密码子。我们能够编码和解码各种文件类型没有错误。
The global demand for digital data is projected to be greater than the supply of semiconductor grade silicon in 2040 [1]. When combined with the need to archive information [2], nucleic acids are being explored as an alternative memory material [1-7]. According to a recent study, the information density of nucleic acid memory (NAM) is one thousand times greater than flash memory and has the ability to last for hundreds of years [1]. Presented here is an algorithm for converting digital data into unique DNA sequences for glacial storage. Biologically inspired, our coding scheme maps hexadecimal characters to sequences of three DNA nucleotides. This mapping avoids repeating sequences and start codons, which could have adverse effects. We were able to encode and decode various file types without error.