Sequel and therapeutic modalities of leptospirosis associated severe pulmonary haemorrhagic syndrome (SPHS); a Sri Lankan experience
Sequel and therapeutic modalities of leptospirosis associated severe pulmonary haemorrhagic syndrome (SPHS); a Sri Lankan experience
复制标题
DOI：
10.1186/s12879-019-4094-0
复制
发表时间：
2019-05-22
影响因子：
3.7
通讯作者：
Agampodi, Suneth
中科院分区：
文献类型：
--
作者：
Herath, Nalaka;Uluwattage, Wimalasiri;Agampodi, Suneth
背景：许多国家都报道了钩端螺旋体相关的严重肺出血性综合征（SPHS）的出现和高病死率。了解SPHS的临床疾病和后续需要大量的研究。本研究的目的是描述斯里兰卡钩端螺旋体病SPHS的特点和不同治疗方法的后果。方法：本研究于2015年6月至2017年12月在斯里兰卡加勒卡拉皮提亚教学医院（THK）进行。港台是南部省主要的三级医疗中心。所有在此期间出现并在香港医院5个医疗单位就诊的确诊钩端螺旋体病病例被纳入本研究。SPHS定义为患者表现为；咯血，动脉低氧血症（急性肺损伤评分）
Background: The emergence of leptospirosis-associated severe pulmonary hemorrhagic syndrome (SPHS) with high case fatality has been reported from many countries. Understanding of clinical disease and sequel of SPHS needs larger studies with adequate numbers. The purpose of this study was to describe the characteristics and sequel by different therapeutic approaches for SPHS in Leptospirosis in Sri Lanka.Methods: This study was conducted at Teaching Hospital-Karapitiya (THK), Galle, Sri Lanka from June 2015 to December 2017. THK is the main tertiary care center for the Southern Province. All confirmed-cases of leptospirosis who presented during this period and were admitted to five medical units of THK were included in this study. SPHS was defined as a patient presenting; haemoptysis, arterial hypoxemia (Acute Lung Injury Score