ANTIBODIES TO GASTROENTERITIS VIRUSES IN CYSTIC-FIBROSIS PATIENTS
ANTIBODIES TO GASTROENTERITIS VIRUSES IN CYSTIC-FIBROSIS PATIENTS
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DOI：
10.1002/jmv.1890090302
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发表时间：
1982-01-01
影响因子：
12.7
通讯作者：
BRAVERMAN, LE
中科院分区：
文献类型：
--
作者：
CUKOR, G;BLACKLOW, NR;BRAVERMAN, LE
包括轮状病毒在内的某些肠道病毒的传染性深受蛋白水解酶的影响。为了检测胰腺酶水平长期下降的囊性纤维化患者是否表现出对胃肠炎病毒的易感性改变，对患者和对照组的血清进行了2种主要病原体抗体检测。囊性纤维化患者轮状病毒抗体水平正常，诺瓦克病毒抗体流行率不变。
Infectivity of certain enteric viruses including rotavirus is profoundly affected by proteolytic enzymes. To test whether cystic fibrosis patients, possessing chronically decreased levels of pancreatic enzymes, show altered susceptibility to gastroenteritis viruses, sera from patients and controls were examined for antibodies to 2 major pathogens. In cystic fibrosis patients, normal rotavirus antibody levels were found and Norwalk virus antibody prevalence was unchanged.