A novel application of nuclear Overhauser enhancement (NOE) in proteins: analysis of correlated events in the exchange of internal labile protons.

A novel application of nuclear Overhauser enhancement (NOE) in proteins: analysis of correlated events in the exchange of internal labile protons.
复制标题

核奥弗豪瑟增强 (NOE) 在蛋白质中的新应用:内部不稳定质子交换中的相关事件分析。

DOI:
10.1016/0006-291x(80)90308-3
复制
发表时间:
1980
影响因子:
3.1
通讯作者:
G. Wagner
G. Wagner
中科院分区:
生物学4区
文献类型:
--
作者:
G. Wagner

文献摘要

被引文献

相似文献

在球状蛋白质中缓慢交换不稳定质子之间的核奥弗豪泽增强的定量评估可以用于决定相关和不相关的交换过程。该方法对于区分EX1和EX2机理是有用的。并对碱性胰蛋白酶抑制剂进行了实验论证。
A quantitative evaluation of nuclear Overhauser enhancements between slowly exchanging labile protons in a globular protein can be used to decide between correlated and uncorrelated exchange processes. The method appears to be useful for distinction of EX1and EX2mechanisms. Demonstrations are given with experiments on the basic pancreatic trypsin inhibitor.