Mitotic control of cancer stem cells.
Mitotic control of cancer stem cells.
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DOI:
10.1158/2159-8290.cd-12-0588
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发表时间:
2013-02
期刊:
影响因子:
28.2
通讯作者:
Rich JN
中科院分区:
文献类型:
--
作者:
Venere M;Miller TE;Rich JN
Cancer stem cells are self-renewing, tumorigenic cells at the apex of tumor hierarchies, and postulated to be quiescent in many tumor types. This issue of Cancer Discovery highlights a study that links the presentation of kinetochores within mitosis to an essential requirement for BUB1B/BubR1, broadening our understanding of the cell-cycle machinery in cancer stem cells.