Advances in stroke: population studies.
Advances in stroke: population studies.
复制标题
中风的进展：人口研究。
作者：
A. Grau;G. Howard
由于缺血性心脏病 (IHD) 和中风有许多共同的危险因素，人们可以推测中风和 IHD 具有相似的地理模式；然而，Kim 和 Johnston 描述了两种疾病的伤残调整生命年 (DALY) 损失在全球范围内存在显着差异。1 对于中风，亚洲大部分地区、东欧和非洲的 DALY 损失≥120/100 000，而北美、西欧和澳大利亚的 DALY 损失率 ≤60/100 000。东欧和北亚的 DALY 损失也非常高 (≥240/100 000) 来自 IHD。总体而言，在 192 个国家中，有 62 个国家因中风造成的伤残调整生命年 (DALY) 损失高于因缺血性心脏病造成的伤残调整生命年 (DALY) 损失，特别是中国，但非洲和南美洲的许多国家也有这种情况。因 IHD 造成 DALY 损失较高的国家/地区（192 个国家中的 74 个）仅略多一些，特别是中东地区，但也有北美、澳大利亚和西欧。与 IHD 相比，国民收入较低、糖尿病患病率较低、平均酒精摄入量较高和肥胖较少的国家因中风导致的伤残调整生命年 (DALY) 损失往往较高。1
Grimaud 及其同事的报告对各国内部中风发病率存在巨大差异的因素进行了研究，他们发现，在法国社会经济地位较低和/或收入不平等程度较高的地区，中风发病率高出三分之一。2 在美国，高社会经济地位和低社会经济地位社区之间的中风风险也存在类似的三分之一（32%）差异。3 与行为风险因素（介导超额 30%）相比，生物风险因素（介导超额 16%）调整后，这些邻里差异的衰减更大，这表明生物风险因素……
With ischemic heart disease (IHD) and stroke sharing many risk factors, one could presume a similar geographic pattern of stroke and IHD; however, Kim and Johnston described remarkable worldwide variations in disability-adjusted life-years (DALY) loss for both diseases.1 For stroke, much of Asia, eastern Europe, and Africa had DALY loss of ≥120/100 000 in contrast to North America, western Europe, and Australia having DALY loss rates ≤60/100 000. Eastern Europe and northern Asia also had strikingly high DALY loss (≥240/100 000) from IHD. Overall, there were 62 of 192 countries with higher DALY loss from stroke than for IHD, particularly for China, but also in many countries in Africa and South America. There were only marginally more countries (74 of 192) with higher DALY loss from IHD, particularly the Middle East, but also North America, Australia, and western Europe. Countries with lower national income, lower prevalence of diabetes, higher average alcohol intake, and less obesity tended to have higher DALY loss from stroke than IHD.1
The contributors to the substantial variations in stroke incidence within countries have been examined by reports including that by Grimaud and colleagues, who showed stroke incidence was as much as one third higher in regions of France with lower levels of socioeconomic status and/or higher levels of income inequality.2 A similar one third difference (32%) in stroke risk was observed between high socioeconomic status and low socioeconomic status neighborhoods in the United States.3 Attenuation of these neighborhood differences was larger with adjustment for biological risk factors (mediated to a 16% excess) than for behavioral risk factors (mediated to a 30% excess), suggesting that biological risk factors …
影响因子：
120.7
作者：
Pan, An;Sun, Qi;Okereke, Olivia I.;Rexrode, Kathryn M.;Hu, Frank B.
通讯作者：
Hu, Frank B.