Symposium on rectal cancer: 2. Local recurrence after surgery for rectal cancer.
Symposium on rectal cancer: 2. Local recurrence after surgery for rectal cancer.
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直肠癌研讨会：2.直肠癌手术后局部复发。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
R. McLeod
中科院分区：
文献类型：
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作者：
R. McLeod
局部复发是直肠癌患者的一个严重并发症，因为它的发生频率高，对生活质量的影响大，而且治疗很少成功。虽然有报道的局部复发率从4%到51%不等，但最近的系列报道的复发率低于10%。多种因素可能影响局部复发率，包括肿瘤的分期和位置。其他预后因素可能很重要，但它们是否为独立的危险因素存在争议。最后，越来越多的证据表明，局部复发率因外科医生而异。这是否由于手术技术或外科专业知识尚不清楚，但为了优化手术效果，建议进行随机对照试验，解决切除程度的问题。
Local recurrence is a serious complication in patients with rectal cancer because of the frequency with which it occurs, its impact on quality of life and the fact that treatment is rarely successful. Although local recurrence rates varying from 4% to 51% have been reported, recent series have reported rates of less than 10%. Various factors may affect the rate of local recurrence, including the stage and location of the tumour. Other prognostic factors may be of importance, but it is controversial whether they are independent risk factors. Finally, there is mounting evidence that the local recurrence rate varies with the surgeon. Whether this is due to the surgical technique or surgical expertise is not clear, but randomized controlled trials addressing the issue of extent of resection are indicated in order to optimize surgical results.