In vivo three-dimensional microelectromechanical endoscopic swept source optical coherence tomography
In vivo three-dimensional microelectromechanical endoscopic swept source optical coherence tomography
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DOI：
10.1364/oe.15.010390
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发表时间：
2007-08-06
期刊：
影响因子：
3.8
通讯作者：
Chen, Zhongping
中科院分区：
文献类型：
--
作者：
Su, Jianping;Zhang, Jun;Chen, Zhongping
在临床应用中，三维(3D)显微图像体积显示了与癌前病变和早期疾病密切相关的组织形态变化，远远好于二维图像。然而，传统的内窥镜只能实现二维表面图像。本文研制了基于旋转式微电子机械系统(MEMS)探头的三维内窥镜显微镜[1]。采用MEMS电机旋转扫描和直线工作台横向运动相结合的方式实现三维螺旋扫描。为了协调MEMS电机在内窥镜中的高自转速度，使用了宽带快扫描激光的光学相干层析成像(OCT)系统。活体显示兔食道和气管的三维图像体积。(C)2007年美国光学学会。
In clinical applications, three-dimensional (3-D) microscopic image volume reveals tissue morphological changes, which are closely related to pre-cancer and early stage disease, much better than two-dimensional images. However, the traditional endoscope only achieves two-dimensional surface images. In this paper, a 3-D endoscopic microscope was developed based on a rotational microelectromechanical system (MEMS) probe [1]. The 3-D helix scan mode was realized by combining a MEMS motor rotational scan and linear stage transversal movement. In order to coordinate the high spin speed of MEMS motor inside the endoscope, an optical coherence tomography (OCT) system with a broadband fast swept laser was used. In vivo 3-D image volumes of rabbit esophagus and trachea were demonstrated. (c) 2007 Optical Society of America.