Glia-neuron interactions at the midline of the developing mammalian brain and spinal cord.
Glia-neuron interactions at the midline of the developing mammalian brain and spinal cord.
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发育中的哺乳动物大脑和脊髓中线的胶质细胞-神经元相互作用。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
J. Silver
中科院分区：
文献类型：
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作者：
J. Silver
发育中的大脑中线是轴突引导决策影响与感觉和运动系统偏侧性相关的基本接线模式的地方。沿中线发育的各种神经胶质结构可能在引导轴突投射到中枢神经系统左侧或右侧方面发挥关键作用。描述了其中一些神经胶质结构及其与轴突的关联。强调了中线轴突引导的分子机制，特别是通过转向信号提供引导线索的排斥因素。
The midline of the developing brain is a place where axon guidance decisions effect the basic wiring pattern related to laterality in both sensory and motor systems. A variety of glial structures that develop along the midline may play crucial roles in directing axons to project to the left or right side of the central nervous system. Several of these glial structures and their association with axons are described. The molecular mechanisms that underlie axons guidance at the midline, in particular, repulsive factors that provide guidance cues via turning signals, are highlighted.