Bioinformatics - A user's perspective
Bioinformatics - A user's perspective
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DOI：
10.1165/ajrcmb.23.6.4291
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发表时间：
2000-12-01
影响因子：
6.4
通讯作者：
Kaminski, N
中科院分区：
文献类型：
--
作者：
Kaminski, N
这篇评论从用户的角度提供了生物信息学的概述。生物信息学，定义为计算机，数据库和计算方法的应用，以管理生物信息，是必不可少的几乎每一个方面的数据管理在现代生物学。基因组序列信息的快速积累以及分析全球基因表达模式的新技术的广泛应用已经造成了信息过载。分子生物学实验室越来越依赖于计算机、大容量数据库、搜索和分析工具以及高质量的互联网连接。目前可用的生物信息学工具进行了讨论，并概述了一般方法。利用本综述中的资源和方法，读者应该能够形成自己对生物信息学的看法，并根据自己的需求定制信息过载的解决方案。
This review provides an overview of bioinformatics from the user's point of view. Bioinformatics, defined as the application of computers, databases, and computational methods to the management of biologic information, is essential for almost every aspect of data management in modern biology. The rapid accumulation of genomic sequence information together with the wide availability of new technologies that analyze global gene expression patterns have created an information overload. Molecular biology labs are increasingly dependent on computers, large-capacity databases, search and analysis tools, and high-quality Internet connections. Currently available bioinformatics tools are discussed and a general approach is outlined. Using the resources and approaches in this review, readers should be able to form their own view of bioinformatics and tailor the solutions to the information overload according to their needs.