A MORPHOLOGY INDEX BASED ON SONOGRAPHIC FINDINGS IN OVARIAN-CANCER
A MORPHOLOGY INDEX BASED ON SONOGRAPHIC FINDINGS IN OVARIAN-CANCER
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DOI：
10.1006/gyno.1993.1238
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发表时间：
1993-10-01
影响因子：
4.7
通讯作者：
VANNAGELL, JR
中科院分区：
文献类型：
--
作者：
DEPRIEST, PD;SHENSON, D;VANNAGELL, JR
开发了基于卵巢肿瘤形态特征的形态指数。具体类别包括肿瘤体积、壁结构和间隔结构。每个类别均制定了评分标准（0-4），每次评估的总分从0-12不等。使用该指数对 121 名接受卵巢肿块剖腹探查术的患者的超声检查进行了评估。 80 个卵巢肿瘤的形态学指数评分<5，且均为良性（阴性预测值，1.000）。在绝经后患者中，形态学指数评分⩾5 的恶性肿瘤阳性预测值为 0.45。所有卵巢恶性肿瘤的壁结构均存在明显异常，且总体积均超过 10 cm3。本研究的结果表明，形态指数是一种具有成本效益的辅助方法，可显着提高经阴道超声检查的特异性和阳性预测值。常规应用形态学指数来筛查超声检查应该减少为检测每个卵巢癌病例而进行的诊断手术的数量。
A morphology index based on morphologic characteristics of ovarian tumors was developed. Specific categories included tumor volume, wall structure, and septal structure. A point scale (0-4) was developed within each category with the total points per evaluation varying from 0-12. Sonograms on 121 patients undergoing exploratory laparotomy for ovarian masses were evaluated using this index. Eighty ovarian tumors had a morphology index score <5, and all were benign (negative predictive value, 1.000). In postmenopausal patients, a morphology index score ⩾5 had a positive predictive value for malignancy of 0.45. All ovarian malignancies had significant abnormalities in wall structure and all had a total volume in excess of 10 cm3. The findings of the present investigation indicate that the morphology index is a cost effective adjuvant method which significantly increases the specificity and positive predictive value of transvaginal sonography. The routine application of a morphology index to screening sonography should decrease the amount of diagnostic surgery performed in order to detect each case of ovarian cancer.