Swallowing and tongue function following treatment for oral and oropharyngeal cancer
Swallowing and tongue function following treatment for oral and oropharyngeal cancer
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DOI：
10.1044/jslhr.4304.1011
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发表时间：
2000-08-01
影响因子：
2.6
通讯作者：
Pierce, M
中科院分区：
文献类型：
--
作者：
Lazarus, CL;Logemann, JA;Pierce, M
本研究检测了13名接受初次放疗+/-化疗的口腔癌或口咽癌受试者和13名年龄和性别匹配的对照受试者的舌功能及其与吞咽的关系。治疗前和治疗后2个月，通过视频透视测量吞咽和舌功能。最大等长力量和耐力在50%的最大力量得到了与低华口腔性能仪器（IOPI）。对照组受试者接受一次测试。所有头颈部肿瘤患者均在治疗前和治疗后2个月进行评估。头颈部癌组治疗前和治疗后2个月的舌功能指标无显著差异。治疗前后，对照组舌强度明显高于头颈部癌组。两组的舌耐力指标无显著差异。头颈部癌组和对照组治疗前后舌强度和耐力以及一些吞咽测量值存在显著相关性。这些相关性包括口腔和咽颞部吞咽测量和口咽吞咽效率。两组之间舌强度的治疗前差异可能与肿瘤体积、疼痛和酸痛有关。治疗后2个月的差异可能与口腔和咽粘膜的放疗+/-化疗变化有关。这项研究为舌强度在口咽吞咽中起作用的假设提供了支持，特别是与吞咽的口腔阶段有关。
This study examined tongue function and its relation to swallowing in 13 subjects with oral or oropharyngeal cancer treated with primary radiotherapy +/- chemotherapy and 13 age- and sex-matched control subjects. Measures of swallowing and tongue function were obtained using videofluoroscopy, pretreatment and 2 months posttreatment. Maximum isometric strength and endurance at 50% of maximum strength were obtained with the lowa Oral Performance instrument (IOPI). Control subjects were tested once. All subjects with head and neck cancer were evaluated pretreatment and 2 months posttreatment. No significant differences were found for the tongue function measures pre- and 2 months posttreatment in the group with head and neck cancer. Significantly higher tongue strength was observed in the control than in the group with head and neck cancer both pre- and posttreatment. No significant differences were Found for the 2 groups for tongue endurance measures. Significant correlations of tongue strength and endurance and some swallow measures were found pre- and posttreatment for the group with head and neck cancer and for the control group. These correlations included oral and pharyngeal temporal swallow measures and oropharyngeal swallow efficiency. Pretreatment differences between the 2 groups in tongue strength were likely related to tumor bulk, pain, and soreness. Two-month posttreatment differences were likely related to radiation +/- chemotherapy changes to the oral and pharyngeal mucosa. This study provides support for the hypothesis that tongue strength plays a role in oropharyngeal swallowing, particularly related to the oral phase of the swallow.