Macrocarpals H, I, and J from the leaves of Eucalyptus globulus

Macrocarpals H, I, and J from the leaves of Eucalyptus globulus
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DOI:
10.1021/np9604994
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发表时间:
1996-09-01
影响因子:
5.1
通讯作者:
Itokawa, H
Itokawa, H
中科院分区:
生物学2区
文献类型:
--
作者:
Osawa, K;Yasuda, H;Itokawa, H

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蓝桉叶的 50% 乙醇提取物产生了 8 种间苯三酚-倍半萜偶联成分,其中包括三种名为大果树 H、I 和 J 的新型化合物。其中一些化合物对口腔病原微生物具有抗菌活性,MIC 值范围为 0.20 μ g/mL 至 6.25 μ g/mL。还注意到这些化合物对葡糖基转移酶活性的抑制。
A 50% EtOH extract of Eucalyptus globulus leaves yielded eight phloroglucinol-sesquiterpene-coupled constituents, including three novel compounds named macrocarpals H, I, and J. Some of these compounds possessed antibacterial activity against oral pathogenic microorganisms with MIC values ranging from 0.20 mu g/mL to 6.25 mu g/mL. Inhibition of glucosyltransferase activity by these compounds was also noted.