Effect of Resistance Training Combined with Beta-Hydroxy-Beta-Methylbutyric Acid Supplements in Elderly Patients with Sarcopenia after Hip Replacement.
Effect of Resistance Training Combined with Beta-Hydroxy-Beta-Methylbutyric Acid Supplements in Elderly Patients with Sarcopenia after Hip Replacement.
复制标题
阻力训练联合β-羟基-β-甲基丁酸补充剂对老年髋关节置换术后肌少症患者的影响。
DOI：
10.1111/os.13208
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发表时间：
2022-04
影响因子：
2.1
通讯作者：
Ma, Xin-long
中科院分区：
文献类型：
--
作者：
Han, Zhe;Ji, Neng-neng;Ma, Jian-xiong;Dong, Qiang;Ma, Xin-long
关键词：
探讨抗阻训练（RT）联合β-羟基-β-甲基丁酸（HMB）治疗老年髋关节置换术后肌减少症的疗效。2018年1月1日至2018年12月31日，200例髋关节置换术后发生股骨颈骨折伴肌肉减少症的老年患者（男性68例，平均年龄76.3岁，女性137例，平均年龄79.1岁）被分配到4组：RT + HMB组、RT组、HMB组和阴性对照组。比较4组患者术前及术后3个月的基线数据、身体成分、握力、Barthel指数（BI）、Harris髋关节评分（HHS）和视觉模拟量表评分（VAS）。共有177名参与者完成了试验，其中HMB + RT组43名，HMB组44名，RT组45名，阴性对照组45名。3个月随访时，HMB + RT组和RT组的身体成分和握力较术前显著改善。HMB组无显著变化，而阴性对照组的测量值显著降低。四组中任何一组的术后BI和HSS均未达到损伤前水平，但术后VAS评分显著改善。然而，四组之间的BI、HSS或VAS无显著差异。在短期随访中，RT（伴或不伴HMB补充）可有效改善髋关节置换术后肌肉减少症老年患者的身体组成和握力。同时，单独使用HMB补充剂也可能有助于防止这些患者的肌肉质量和握力下降。RT联合或不联合HMB均能有效改善髋关节置换术后肌肉减少症老年患者的体成分和握力。尽管如此，HMB补充剂也可能有助于防止这些患者的肌肉质量和握力下降。
To evaluate the efficacy of resistance training (RT) combined with beta‐hydroxy‐beta‐methylbutyric acid (HMB) in the treatment of elderly patients with sarcopenia after hip replacement. From January 1, 2018 to December 31, 2018, 200 elderly patients (68 men, mean age 76.3 years and 137 women, mean age 79.1 years) who experienced femoral neck fracture with sarcopenia after hip arthroplasty were assigned to four groups: RT + HMB group, RT group, HMB group, and negative control group. Baseline data, body composition, grip strength, Barthel index (BI), Harris hip score (HHS), and visual analog scale score (VAS) were compared among the four groups before and 3 months after surgery. A total of 177 participants completed the trial, including 43 in the HMB + RT group, 44 in the HMB group, 45 in the RT group, and 45 in the negative control group. At the 3‐month follow‐up, the body composition and grip strength of the HMB + RT group and RT group were significantly improved compared with those before operation. The HMB group had no significant change, while the measures in the negative control group significantly decreased. Postoperative BI and HSS did not reach pre‐injury levels in any of the four groups, but postoperative VAS score was significantly improved. However, there was no significant difference in BI, HSS, or VAS among the four groups. RT, with or without HMB supplementation, can effectively improve body composition and grip strength in elderly patients with sarcopenia after hip replacement at short‐term follow‐up. Simultaneously, use of exclusive HMB supplementation alone may also help to prevent decreases in muscle mass and grip strength in these patients. RT, with or without HMB supplementation, can effectively improve body composition and grip strength in elderly patients with sarcopenia after hip replacement. Still, HMB supplementation may also help to prevent decreases in muscle mass and grip strength in these patients.
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影响因子：
--
作者：
Backer, Henrik C;Wu, Chia H;Perka, Carsten
通讯作者：
Perka, Carsten
影响因子：
3.9
作者：
Avola M;Mangano GRA;Testa G;Mangano S;Vescio A;Pavone V;Vecchio M
通讯作者：
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影响因子：
2.1
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通讯作者：
Pulle, Chrys Ranjeev
影响因子：
2.5
作者：
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通讯作者：
Ebraheim, Nabil
影响因子：
6.1
作者：
Duan, Yehui;Li, Fengna;Yin, Yulong
通讯作者：
Yin, Yulong