The influence of bileaflet prosthetic aortic valve orientation on the blood flow patterns in the ascending aorta
The influence of bileaflet prosthetic aortic valve orientation on the blood flow patterns in the ascending aorta
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DOI：
10.1016/j.medengphy.2018.07.013
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发表时间：
2018-10-01
影响因子：
2.2
通讯作者：
Holzner, Markus
中科院分区：
文献类型：
--
作者：
Gulan, Utku;Holzner, Markus
我们使用解剖学上精确的主动脉，在生理血流条件下以两个不同方向植入机械假体主动脉瓣，研究升主动脉中的三维脉动主动脉血流。我们执行 3D 粒子跟踪测速测量来评估相位平均和脉动速度模式以及剪切应力。 St Jude Medical 人工心脏瓣膜被植入解剖学精确的主动脉硅胶模型中，该模型是通过对健康先证者在两个不同方向的高分辨率磁共振成像获得的。我们的结果表明，机械人工瓣膜方向对局部动能和剪切应力分布有相当大的影响，但对空间平均动能 (10%) 和剪切应力 (15%) 影响较小。我们表明，阀门方向在壁剪应力和涡流结构的空间分布中起着独特的作用。我们表明，我们的结果与文献中的计算机和体外研究具有良好的一致性，提供了生理流动条件下不同双叶人工瓣膜方向的整个心动周期的完整 3D 动能和剪切应力信息。 (C) 2018 年 IPEM。由爱思唯尔有限公司出版。保留所有权利。
We investigate three-dimensional pulsatile aortic flow in the ascending aorta with mechanical prosthetic aortic valve implanted at two different orientations under physiological flow conditions using an anatomically accurate aorta. We perform 3D Particle Tracking Velocimetry measurements to assess the phase averaged and fluctuating velocity patterns as well as the shear stresses. A St Jude Medical prosthetic heart valve is implanted in an anatomically accurate silicone model of an aorta obtained from high resolution magnetic resonance imaging of a healthy proband at two different orientations. Our results show that the mechanical prosthetic valve orientation has considerable impact on the local kinetic energy and shear stress distributions but minor effects on the spatially averaged kinetic energy (10%) and shear stresses (15%). We show that the valve orientation plays a distinct role in spatial distribution of wall shear stresses and vortical structures. We show that our results, which show good agreement with the in silico and in vitro studies in the literature, provide full 3D kinetic energy and shear stress information over the entire cardiac cycle for different bileaflet prosthetic valve orientations under physiological flow conditions. (C) 2018 IPEM. Published by Elsevier Ltd. All rights reserved.