EPIZOOTIC GASTRITIS ASSOCIATED WITH GASTRIC SPIRAL BACILLI IN CHEETAHS (ACINONYX-JUBATUS)
EPIZOOTIC GASTRITIS ASSOCIATED WITH GASTRIC SPIRAL BACILLI IN CHEETAHS (ACINONYX-JUBATUS)
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DOI：
10.1177/030098589303000107
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发表时间：
1993-01-01
影响因子：
2.4
通讯作者：
MORGAN, DR
中科院分区：
文献类型：
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作者：
EATON, KA;RADIN, MJ;MORGAN, DR
爆发的呕吐在一组圈养猎豹（Acinonyx jubatus）进行了调查，组织学检查发现慢性胃炎的淋巴细胞和众多的浆细胞和上皮糜烂浸润的特点。滤泡状滤泡、球状白细胞、散在中性粒细胞和（1只动物）胃腺肿胀是不一致的结果。此外，三只猎豹的尸检显示胃粘膜增生。在受感染的猎豹的胃里发现了两种细菌。在胃粘液和Warthin-Starry染色的粘膜切片中观察到许多长的、紧密盘绕的能动胃肠道样微生物。这些细菌不能培养，但从受感染的猎豹的胃粘膜匀浆中传播到常规小鼠。超微结构检查发现这些细菌的螺旋丝。此外，还分离出一种较小的螺杆菌。该微生物可在微需氧条件下体外培养。这些细菌中的一种或两种可能是造成这些猎豹胃炎的原因。
An outbreak of vomiting in a group of captive cheetahs (Acinonyx jubatus) was investigated, and histologic examination revealed chronic gastritis characterized by infiltration of lymphocytes and numerous plasma cells and epithelial erosions. Lymphoid follicles, globule leukocytes, scattered neutrophils, and (in one animal) abscessed gastric glands were inconsistent findings. In addition, necropsy of three cheetahs revealed gastric mucosal hyperplasia. Two kinds of bacteria were identified in the stomachs of infected cheetahs. Numerous long, tightly coiled motile Gastrospirillum-like organisms were seen in gastric mucus and in Warthin-Starry-stained sections of mucosa. These bacteria could not be cultured but were transmitted to conventional mice in homogenates of gastric mucosa from infected cheetahs. Ultrastructural examination revealed helical filaments on some of these bacteria. In addition, a smaller Helicobacter sp. was isolated. This organism, could be cultured in vitro under microaerophilic conditions. One or both of these bacterial species was probably responsible for the gastritis in these cheetahs.