NEW METHODS OF MEASURING RATE OF AQUEOUS FLOW IN MAN WITH FLUORESCEIN
NEW METHODS OF MEASURING RATE OF AQUEOUS FLOW IN MAN WITH FLUORESCEIN
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DOI：
10.1016/s0014-4835(66)80009-x
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发表时间：
1966-01-01
影响因子：
3.4
通讯作者：
MAURICE, DM
中科院分区：
文献类型：
--
作者：
JONES, RF;MAURICE, DM
本文介绍了两种测定人眼房水荧光素损失率的方法。通过离子电渗法将染料引入角膜，并使用裂隙灯荧光光度计在眼睛中进行评估。在第一种方法中，观察前房中荧光素浓度的时间过程，从中得出其在房中的周转率。在第二种方法中，测量眼睛的总荧光与房水的总荧光的比率导致直接评估房水流速。的错误和局限性的方法进行了讨论，并得出结论，第二种方法，虽然一般更可靠，是不适用于蓝眼睛的主题。在其他情况下，两种方法得到的结果之间有很好的一致性。在一小组年轻的正常志愿者中，第一种方法测得的平均周转率为0.015 min，第二种方法测得的平均流速为2.5 [mu]l/min。
Two methods of determining the rate of loss of fluorescein from the aqueous humor in man are described. The dye is introduced into the cornea by means of iontophoresis and estimated in the eye with the slit-lamp fluorophotometer. In the 1st method the time course of the fluorescein concentration in the anterior chamber is observed, from which its turnover rate in the chamber is derived. In the second method measurements of the ratio of the total fluorescence of the eye to that of the aqueous humour lead to a direct evaluation of the aqueous flow rate. The errors and limitations of the methods are discussed and it is concluded that the second method, though generally more reliable, is inapplicable to blue-eyed subjects. In other cases there is good accordance between the results obtained by the two methods. In a small group of young normal volunteers the mean turnover rate found by the first method was 0.015 min and the mean rate of flow by the 2nd method 2.5 [mu]l/min.