Speckle in optical coherence tomography

Speckle in optical coherence tomography
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DOI:
10.1117/1.429925
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发表时间:
1999-01-01
影响因子:
3.5
通讯作者:
Yung, KM
Yung, KM
中科院分区:
医学3区
文献类型:
--
作者:
Schmitt, JM;Xiang, SH;Yung, KM

文献摘要

被引文献

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散斑是光学相干层析成像(OCT)中测量的干涉信号的有限空间频率带宽的自然结果。在高散射生物组织的图像中,散斑具有作为噪声源和作为关于组织微结构的信息的载体的双重作用。本文的前半部分概述了OCT中散斑的起源、统计特性和分类。根据样本光束的相位和振幅扰动定义了信号携带散斑和信号退化散斑的概念。在论文的后半部分,四个散斑抑制方法-偏振分集,空间复合,频率复合,和数字信号处理-进行了讨论,并简要分析了每种方法的潜在有效性的帮助下的例子。最后,提出了有待进一步研究的问题。(C)1999年光电仪器工程师学会[S1083-3668(99)01401-X]。
Speckle arises as a natural consequence of the limited spatial-frequency bandwidth of the interference signals measured in optical coherence tomography (OCT). In images of highly scattering biological tissues, speckle has a dual role as a source of noise and as a carrier of information about tissue microstructure. The first half of this paper provides an overview of the origin, statistical properties, and classification of speckle in OCT. The concepts of signal-carrying and signal-degrading speckle are defined in terms of the phase and amplitude disturbances of the sample beam. In the remaining half of the paper, four speckle-reduction methods-polarization diversity, spatial compounding, frequency compounding, and digital signal processing-are discussed and the potential effectiveness of each method is analyzed briefly with the aid of examples. Finally, remaining problems that merit further research are suggested. (C) 1999 Society of Photo-Optical Instrumentation Engineers [S1083-3668(99)01401-X].