Neuropsychiatric involvement in systemic lupus erythematosus.
Neuropsychiatric involvement in systemic lupus erythematosus.
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DOI：
10.1007/s11926-002-0043-8
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发表时间：
2002-08-01
影响因子：
5
通讯作者：
Brey, Robin L
中科院分区：
文献类型：
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作者：
Hermosillo-Romo, David;Brey, Robin L
系统性红斑狼疮(SLE)患者的中枢和外周神经系统表现的正确诊断可能具有挑战性，因为患者可能存在许多与SLE相关和非SLE相关的过程。美国风湿病学会(ACR)公布了19种神经精神系统性红斑狼疮(NPSLE)综合征的病例定义，并仔细注意重要的排除标准。这些标准是为研究目的而制定的，但对患有神经系统功能障碍的患者的临床医生可能有帮助。这份报告回顾了有关ACR NPSLE标准的应用以及种族和病程对NPSLE综合征发展的影响的数据。认知功能障碍和精神障碍是最常见的两种表现。对神经系统综合征的治疗和治疗也进行了讨论。
The correct diagnosis of central and peripheral nervous system manifestations in patients with systemic lupus erythematosus (SLE) can be challenging because of many SLE-related and non-SLE-related processes that can be present in a patient. The American College of Rheumatology (ACR) has published case definitions for 19 neuropsychiatric SLE (NPSLE) syndromes, with careful attention to important exclusion criteria. These criteria were developed for research purposes but can be helpful to clinicians with a patient who has nervous system dysfunction. This report reviews the data regarding the application of the ACR NPSLE criteria and the influence of ethnicity and disease duration on the development of NPSLE syndromes. Cognitive dysfunction and psychiatric disorders are the two most common manifestations. The work-up and treatment of nervous system syndromes are also discussed.