Prediction of post-treatment retinal sensitivity by baseline retinal perfusion density measurements in eyes with branch retinal vein occlusion
Prediction of post-treatment retinal sensitivity by baseline retinal perfusion density measurements in eyes with branch retinal vein occlusion
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DOI：
10.1038/s41598-020-66708-0
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发表时间：
2020-06-15
影响因子：
4.6
通讯作者：
Murata, Toshinori
中科院分区：
文献类型：
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作者：
Rachima, Soraya;Hirabayashi, Kazutaka;Murata, Toshinori
在这项研究中，我们调查黄斑敏感性和视网膜灌注密度（PD）之间的纵向相关性受视网膜分支静脉阻塞。视网膜敏感性采用微视野计测量，PD采用光学相干断层扫描血管造影术测量。我们还研究了抗血管内皮生长因子（VEGF）治疗后1个月的PD是否是抗VEGF治疗成功的黄斑水肿1年后视网膜敏感性的预测因子。研究了基线（1 M）以及6个月和12个月时视网膜敏感度和PD测量值之间的相关性。视网膜敏感度与PD在所有时间点均呈显著正相关（基线（1M），r= 0.67，P
In this study, we investigated the longitudinal correlation between macular sensitivity and perfusion density (PD) in retinas affected by branch retinal vein occlusion. Retinal sensitivity was measured using microperimetry and PD was measured by optical coherence tomography angiography. We also investigated the possibility that the PD, 1 month after anti-vascular endothelial growth factor (VEGF) treatment, is a predictor of retinal sensitivity after 1 year of successful macular oedema management with anti-VEGF. The correlation between measurements of retinal sensitivity and PD at baseline (1 M) and at 6 and 12 months were investigated. There was a significant positive correlation between retinal sensitivity and PD at all time points (baseline (1 M), r=0.67, P