Chemical Exposures : Lessons Learned as a Result of Finding New Human Teratogens Congenital Minamata Disease

Chemical Exposures : Lessons Learned as a Result of Finding New Human Teratogens Congenital Minamata Disease
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化学物质暴露:发现新的人类致畸物质的经验教训 先天性水俣病

DOI:
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发表时间:
2006
期刊:
影响因子:
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通讯作者:
J. Cordero
J. Cordero
中科院分区:
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文献类型:
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作者:
J. Cordero

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灾难被定义为人类生态的破坏超出了社区正常运作的能力。人们对自然灾害对生殖结果的不利影响知之甚少。水俣湾灾难等人为因素造成的一些灾难可以得出重要的教训。不良生殖后果包括不孕、早期流产、死产、先天畸形以及脑瘫和智力低下等严重发育障碍。最近发生的切尔诺贝利和博帕尔爆炸等灾难提供了重要的教训,即需要准确、可靠的信息来了解产前暴露对不良生殖结果的风险。研究不良生殖结果和灾害的问题需要周密计划的方法。它应包括对不良生殖结果的早期监测、对直接和间接影响造成的灾难风险的分析研究、衡量早期妊娠流产的敏感方法以及评估发育障碍等结果的长期随访计划。
A disaster has been defined as a disruption of human ecology that exceeds the capacity of the community to function normally. Little is known about the adverse effects of natural disasters on reproductive outcomes. Important lessons can be derived from several disasters caused by human factors, such as the Minamata Bay disaster. Adverse reproductive outcomes include infertility, early pregnancy loss, stillbirths, congenital malformations, and serious developmental disabilities such as cerebral palsy and mental retardation. Recent disasters like the Chernobyl and Bhopal explosions have provided important lessons on the need for accurate and sound information about the risk of prenatal exposures for adverse reproductive outcomes. To study questions of adverse reproductive outcomes and disasters requires a well-planned approach. It should include early development of surveillance for adverse reproductive outcomes, analytic studies on the risk of disasters from direct and indirect effects, sensitive methods to measure early pregnancy loss, and long-term follow-up programs to assess outcomes such as developmental disabilities.
DOI: 10.1093/oxfordjournals.aje.a114417
发表时间: 1986-09-01
影响因子: 5
作者:
BAIRD, DD;WILCOX, AJ;WEINBERG, CR
通讯作者: WEINBERG, CR
建议限制孕妇使用热水浴缸和桑拿浴室。
DOI: --
发表时间: 1981
影响因子: 14.6
作者:
Harvey,MA;McRorie,MM;Smith,DW
通讯作者: Smith,DW