Comparison between PHITS and GEANT4 Simulations of the Heavy Ion Beams at the BEVALAC at LBNL and the Booster Accelerator at BNL.

Comparison between PHITS and GEANT4 Simulations of the Heavy Ion Beams at the BEVALAC at LBNL and the Booster Accelerator at BNL.
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DOI:
10.1016/j.lssr.2021.03.002
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发表时间:
2021-05
影响因子:
2.5
通讯作者:
Cucinotta FA
Cucinotta FA
中科院分区:
生物学3区
文献类型:
--
作者:
Pak S;Cucinotta FA

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由于与x射线等传统辐射相比,重带电粒子具有更好的剂量-深度分布,因此已被讨论用于临床应用。此外,银河宇宙射线(GCR)中的高电荷和高能离子(HZE)对前往地球月球或火星的载人航天任务构成重要的健康风险。重离子加速器实验用于放射生物学研究;然而,轨道段或布拉格峰辐照的数值模拟由于光束线和剂量系统的细节而变得复杂。当前工作的目标是支持劳伦斯伯克利国家实验室(LBNL)历史放射生物学数据的生物物理建模,以及布鲁克海文国家实验室(BNL)设施(美国宇航局空间辐射实验室(NSRL))的最新结果。本文利用基于蒙特卡罗的PHITS和GEANT4模拟工具,在LBNL和BNL的几何结构中,对4He、12C和20Ne粒子的铺展布拉格峰(SOBP)和56Fe离子的布拉格曲线进行了数值模拟。计算并讨论了靶材料中主要粒子和次要粒子(包括中子和光子)的剂量贡献。结果表明,对于重于4He离子的初级离子,GEANT4模拟中次级离子的贡献大于PHITS模拟,PHITS模拟中的统计波动更小,对中子的预测更好。据估计,中子和伽马射线对这些光束的吸收剂量贡献不大。
Heavy charged particles have been discussed for clinical use due to their superior dose-depth distribution compared to conventional radiation such as X-rays. In addition, high-charge and energy (HZE) ions in galactic cosmic rays (GCR) present important health risks for crewed space missions to the Earth’s moon or Mars. Experiments at heavy ion accelerators are used in radiobiology studies; however, numerical simulations of track segment or Bragg peak irradiations are complicated by the details of the beam-line and dosimetry systems. The goal of the present work is in support of biophysics modeling of historical radiobiology data at Lawrence Berkeley National Laboratory (LBNL) and more recent results from the Brookhaven National Lab (BNL) facility (NASA Space Radiation Lab (NSRL)). In this work, the Spread-Out Bragg Peak (SOBP) of 4He, 12C, and 20Ne particles, and a Bragg curve of 56Fe ion have been simulated numerically in the geometries of LBNL and BNL using the Monte-Carlo based PHITS and GEANT4 simulation toolkits. The dose contributions of primary particles and secondary particles, including neutrons and photons, in the target material are computed and discussed as well. Comparisons suggest more contributions of secondaries in GEANT4 simulations compared to PHITS simulations for primary ions heavier than 4He ions, and less statistical fluctuation and better prediction of neutrons in PHITS simulations. Neutrons and gamma-rays are estimated to make minor contributions to absorbed doses for these beams.
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