An Updated Review of Ciguatera Fish Poisoning: Clinical, Epidemiological, Environmental, and Public Health Management.
An Updated Review of Ciguatera Fish Poisoning: Clinical, Epidemiological, Environmental, and Public Health Management.
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DOI：
10.3390/md15030072
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发表时间：
2017-03-14
期刊：
影响因子：
5.4
通讯作者：
Fleming LE
中科院分区：
文献类型：
--
作者：
Friedman MA;Fernandez M;Backer LC;Dickey RW;Bernstein J;Schrank K;Kibler S;Stephan W;Gribble MO;Bienfang P;Bowen RE;Degrasse S;Flores Quintana HA;Loeffler CR;Weisman R;Blythe D;Berdalet E;Ayyar R;Clarkson-Townsend D;Swajian K;Benner R;Brewer T;Fleming LE
雪卡鱼中毒 (CFP) 是世界上最常报告的海鲜毒素疾病。它对人类健康、社会和经济造成重大影响。这种疾病会产生一系列复杂的胃肠道、神经和神经心理以及心血管症状，可能持续数天、数周或数月。本文是对 CFP 的总体综述，包括接触雪卡毒素 (CTX) 对人类健康的影响、诊断、CFP 的人类病理生理学、治疗、鱼类 CTX 检测、疾病的流行病学、全球范围、预防、未来方向以及对临床医生和患者的建议。它更新并扩展了 Friedman 等人之前发表的 CFP 评论。 （2008）并讨论了新的见解和相关的新兴全球主题，例如气候和环境变化、国际市场问题以及 CFP 的社会经济影响。它还为 CFP 提供了一个拟议的通用病例定义，旨在考虑不同地理区域症状表现的差异。重申了自上次审查以来重要但未改变的信息。本文面向广大读者，包括资源和渔业管理者、商业和休闲渔民、公共卫生官员、医疗专业人员和其他相关方。
Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the world. It causes substantial human health, social, and economic impacts. The illness produces a complex array of gastrointestinal, neurological and neuropsychological, and cardiovascular symptoms, which may last days, weeks, or months. This paper is a general review of CFP including the human health effects of exposure to ciguatoxins (CTXs), diagnosis, human pathophysiology of CFP, treatment, detection of CTXs in fish, epidemiology of the illness, global dimensions, prevention, future directions, and recommendations for clinicians and patients. It updates and expands upon the previous review of CFP published by Friedman et al. (2008) and addresses new insights and relevant emerging global themes such as climate and environmental change, international market issues, and socioeconomic impacts of CFP. It also provides a proposed universal case definition for CFP designed to account for the variability in symptom presentation across different geographic regions. Information that is important but unchanged since the previous review has been reiterated. This article is intended for a broad audience, including resource and fishery managers, commercial and recreational fishers, public health officials, medical professionals, and other interested parties.