Effects of the process dynamics in picosecond laser ablation of soft tissues
Effects of the process dynamics in picosecond laser ablation of soft tissues
复制标题
皮秒激光软组织消融过程动力学的影响
DOI：
10.1117/12.2610104
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Beck R
中科院分区：
文献类型：
--
作者：
Beck R
介绍了利用皮秒激光脉冲成功地对临床相关组织模型进行激光消融的情况。这是克服传统电烙工具在精度和热损伤方面的限制的潜在替代方案。该过程的高速成像与处理后组织形态的组织病理学分析的相关性使得能够优化组织去除率，同时避免不利的空化效应，以将附带的热损伤保持在最小程度。有效的组织去除上皮激光消融结肠组织和翻译这一过程对头部和颈部手术和脑外科手术进行了讨论。
The successful laser ablation of clinically relevant tissue models by means of picosecond laser pulses is presented. This is a potential alternative to overcome limitations of conventional electrocautery tools in terms of precision and thermal damage. The correlation of high-speed imaging of the process and a histopathological analysis of the post-process tissue morphology enables optimisation of the tissue removal rate whilst avoiding adverse cavitation effects in order to keep the collateral thermal damage to a minimum. Effective tissue removal is presented for the epithelial laser ablation of colonic tissue and the translation of this process towards head and neck surgery and brain surgery is discussed.