Comparison of diphosphonate effects on enamel in vitro and in vivo.
Comparison of diphosphonate effects on enamel in vitro and in vivo.
复制标题
二膦酸盐对体外和体内牙釉质影响的比较。
DOI：
10.1159/000260688
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发表时间：
1983
期刊：
影响因子：
4.2
通讯作者：
Koulourides,T
中科院分区：
文献类型：
--
作者：
Wöltgens,JH;Koulourides,T
采用体外和体内双膦酸盐溶液（EHDP）处理牙釉质。EHDP在体外抑制再矿化，但加入牙釉质后增加抗酸能力。体内EHDP的作用不同。这可以用体外实验中发现的EHDP对牙菌斑中酸形成的影响和表面活性唾液分子对EHDP对脱矿和再矿化的抑制作用的可加性来解释。
Enamel was exposed to diphosphonate solutions (EHDP) in vitro and in vivo. EHDP inhibited remineralization in vitro, but increased the resistance against acid when incorporated in the enamel. In vivo EHDP acted differently. This may be explained by additivity of the effect of EHDP on acid formation in plaque and the effect of surface active salivary molecules to the inhibition of EHDP on de- and remineralization as was found in the in vitro experiments.