The secondary structures of the Xenopus laevis and human mitochondrial small ribosomal subunit RNA are similar
The secondary structures of the Xenopus laevis and human mitochondrial small ribosomal subunit RNA are similar
复制标题
非洲爪蟾和人类线粒体小核糖体亚基RNA的二级结构相似
DOI：
10.1016/0014-5793(86)80431-8
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发表时间：
1986
期刊：
影响因子：
3.5
通讯作者：
G. Brun
中科院分区：
文献类型：
--
作者：
D. Dunon;G. Brun
对Xenopuslaev线粒体核糖体小亚基RNA基因的核苷酸序列进行了广泛的校正[Roe et al.（1985）J. Biol. Chem. 260，9759 - 9774]。我们发现了一个142个核苷酸的额外片段，并描述了分散在基因中的25个核苷酸差异。该X.绵羊线粒体12 S rRNA基因与牛线粒体相同基因的同源性为80%。我们提出了一个新的二级结构的产品的X。拉维斯金与Roe等人的发现相反，我们观察到与人线粒体12 S rRNA基因产物相同的茎和环的一般结构。另一方面，线粒体和细胞质的小亚基rRNA之间的结构同源性观察X。laevis似乎低得多。这些结果有力地表明，动物脊椎动物线粒体DNA遵循相同的进化途径。
Extensive corrections of the nucleotide sequence of theXenopuslaevismitochondrial small ribosomal subunit RNA gene [Roe et al. (1985) J. Biol. Chem. 260, 9759‐9774] are reported. We found an additional fragment of 142 nucleotides and describe 25 nucleotide differences scattered in the gene. The nucleotide sequence of theX. laevismitochondrial 12 S rRNA gene presents 80% homology with that of the same gene of bovine mitochondrion. We propose a new secondary structure for the product of theX. laevisgene. Contrary to the finding of Roe et al., we observed the same general organization of stems and loops as for the human mitochondrial 12 S rRNA gene product. On the other hand, the structural homology observed between the mitochondrial and cytoplasmic small subunit rRNAs ofX. laevisappears much lower. These results strongly suggest that animal vertebrate mitochondrial DNAs have followed the same evolutionary pathway.
影响因子：
16.6
作者：
D. Clayton
通讯作者：
D. Clayton