OPTIMUM BIASED COIN DESIGNS FOR SEQUENTIAL CLINICAL-TRIALS WITH PROGNOSTIC FACTORS
OPTIMUM BIASED COIN DESIGNS FOR SEQUENTIAL CLINICAL-TRIALS WITH PROGNOSTIC FACTORS
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DOI：
10.1093/biomet/69.1.61
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发表时间：
1982-01-01
期刊：
影响因子：
2.7
通讯作者：
ATKINSON, AC
中科院分区：
文献类型：
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作者：
ATKINSON, AC
DA-最优实验设计的理论是用来提供有偏硬币型设计的序贯临床试验中存在或不存在，预后因素。这些设计避免了早期方案的许多任意特征。
The theory of DA-optimum design of experiments is used to provide designs of the biased coin type for sequential clinical trials in the presence or absence, of prognostic factors. The designs avoid many arbitrary features of earlier schemes.