Electron transfer reactions of high-potential iron-sulfur proteins and c-type cytochromes.
Electron transfer reactions of high-potential iron-sulfur proteins and c-type cytochromes.
复制标题
高电位铁硫蛋白和c型细胞色素的电子转移反应。
DOI：
10.1021/bi00562a002
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发表时间：
1980
期刊：
影响因子：
2.9
通讯作者：
Cusanovich,MA
中科院分区：
文献类型：
--
作者：
Mizrahi,IA;Cusanovich,MA
Issac A. Mizrahi* 和 Michael A. Cusanovich* 摘要：生物氧化还原蛋白的电子转移研究通常集中于特定蛋白质与非生理氧化剂和/或还原剂的相互作用。这种方法虽然有价值，但受到非生理反应物的大小和化学性质的限制。为了进一步了解生物电子转移，我们研究了两个高电位铁硫蛋白 (HIPIP) 与来自红色红螺菌、沼泽红假单胞菌、荚膜红假单胞菌和球形红假单胞菌的线粒体细胞色素 c（马心）和细菌细胞色素 c2 的相互作用。根据各种 HIPIP 和细胞色素之间的电子转移动力学，这种相互作用似乎比用非生理反应物观察到的相互作用更为复杂。我们的结论是（1）特定地点
Issac A. Mizrahi* and Michael A. Cusanovich* abstract: Studies of electron transfer by biological oxida-tion-reduction proteins frequently focus on the interaction of a particular protein with nonphysiologicaloxidants and/or reductants. This approach, although valuable, is limited by the size and chemistry of the nonphysiological reactants. To further the understanding of biological electron transfer, we have investigated theinteraction of two examples of highpotential iron-sulfur proteins (HIPIP’s) with mitochondrial cytochrome c (horse heart) and bacterial cytochrome c2 from Rhodospirillum rubrum, Rhodopseudomonas palustris, Rhodopseudomonas capsulata, and Rhodopseudomonas sphaeroides. On the basis of the kinetics of electron transfer between the various HIPIP’s and cytochromes, it appears that the interactions are more complex than those observed with nonphysiological reactants. We conclude that (1) specific sites