Stem cell regulation in the Arabidopsis shoot apical meristem.
Stem cell regulation in the Arabidopsis shoot apical meristem.
复制标题
DOI：
10.1016/j.pbi.2005.09.010
复制
发表时间：
2005-12
影响因子：
9.5
通讯作者：
L. Williams;J. Fletcher
中科院分区：
文献类型：
--
作者：
L. Williams;J. Fletcher
高等植物的气生结构是在整个生命周期中通过位于生长的茎尖（顶端分生组织）的干细胞的活动动态产生的。干细胞不断分裂以更新自身，并为叶、茎和花的形成提供细胞。干细胞的维持是由顶端干细胞和底层组织中心之间的细胞间通讯控制的。最近的进展已在理解的机制，诱导茎干细胞的身份，并控制的位置和大小的组织中心。染色质重塑因子、转录因子和microRNA等元件新近参与了这些调控过程。这些进展提供了一个框架，我们了解如何整合信号，以指定和定位茎顶端分生组织中的干细胞龛。
The aerial structure of higher plants is generated dynamically throughout the life cycle through the activity of stem cells that are located at the growing shoot tip, the apical meristem. The stem cells continuously divide to renew themselves and provide cells for leaf, stem and flower formation. Stem cell maintenance is governed by intercellular communication between the apical stem cells and the underlying organizing centre. Recent advances have been made in understanding the mechanisms that induce shoot stem cell identity, and that control the position and size of the organizing centre. Elements such as chromatin remodeling factors, transcription factors and microRNAs are newly implicated in these regulatory processes. These advances provide a framework for our understanding of how signals are integrated to specify and position the stem cell niche in the shoot apical meristem.