A noninvasive mucinous cystic neoplasm with intermediate-grade dysplasia of the pancreas and extensive squamous metaplasia: a case report with clinicopathological correlation
A noninvasive mucinous cystic neoplasm with intermediate-grade dysplasia of the pancreas and extensive squamous metaplasia: a case report with clinicopathological correlation
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伴有胰腺中度发育不良和广泛鳞状化生的非侵袭性粘液囊性肿瘤：具有临床病理学相关性的病例报告。
DOI：
10.1186/1746-1596-7-89
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发表时间：
2012-07-31
影响因子：
2.6
通讯作者：
Wang, Zhe
中科院分区：
文献类型：
--
作者：
Li, Peifeng;Wang, Yingmei;Wang, Zhe
在胰腺的非侵袭性粘液性囊性肿瘤(MCN)中出现鳞状化生是极其罕见的。我们描述了一位39岁的中国女性患者，她有5年的左上腹部肿块缓慢增长和18个月的手术伤口渗出史。患者因初诊为“胰腺囊肿”，先后行囊性空肠吻合术、剖腹探查及胰腺远端切除术。组织学切片显示柱状粘液分泌上皮形成小乳头状突起，广泛可见鳞状化生。因此最终诊断为“非侵袭性MCN伴胰腺中度不典型增生和广泛的鳞状化生”。胰腺的鳞状细胞成分可能来自多能干细胞，并可能与囊肠吻合术有关。虚拟幻灯片：本文的虚拟幻灯片(S)可以在这里找到http://www.diagnosticpathology.diagnomx.eu/vs/1322364365718540
Squamous metaplasia presenting in noninvasive mucinous cystic neoplasm (MCN) of the pancreas is extremely rare. We described a case of 39-year-old Chinese female with a 5-year history of a slow growing mass in the left upper abdomen and an 18-month history of surgical incision exudation. The patient underwent cystojejunostomy, laparotomy and distal pancreatectomy consecutively because of the initial diagnosis of "pancreatic cyst". The histological section showed columnar mucin-producing epithelium formed small papillary projections and extensively visible squamous metaplasia. Therefore the diagnosis of "noninvasive MCN with intermediate-grade dysplasia of the pancreas and extensive squamous metaplasia" was made finally. The squamous component of the pancreas may be derived from pluripotent stem cells, and may be in association with cystojejunostomy.Virtual slides: The virtual slide(s) for this article can be found here http://www.diagnosticpathology.diagnomx.eu/vs/1322364365718540