Club drugs and HIV infection: A review
Club drugs and HIV infection: A review
复制标题
DOI：
10.1086/503259
复制
发表时间：
2006-05-15
影响因子：
11.8
通讯作者：
Guzman, R
中科院分区：
文献类型：
--
作者：
Colfax, G;Guzman, R
在艾滋病毒感染者和艾滋病毒感染高危人群中，俱乐部吸毒很常见。俱乐部药物具有无数的急性和慢性医疗后果。在过去15年中，与俱乐部毒品有关的急诊和药物使用治疗的入院人数急剧增加。大多数流行病学数据支持俱乐部药物在增加性风险行为中的作用，一些研究表明使用某些俱乐部药物与艾滋病毒感染之间存在独立关联。俱乐部药物对艾滋病毒疾病进展的直接影响仍有待确定;然而，俱乐部药物可能与某些逆转录病毒药物相互作用，并与药物依从性下降有关。临床医生应询问所有患者关于俱乐部药物使用的模式，告知患者与俱乐部药物使用相关的风险，并在有临床指征时将患者推荐给适当的行为治疗计划。
Club drug use is common among populations with human immunodeficiency virus (HIV) and populations at high risk for HIV infection. Club drugs have a myriad of acute and chronic medical consequences. Club drug-related visits to the emergency department and admissions for treatment of substance use have increased dramatically over the past 15 years. Most epidemiological data support the role of club drugs in increasing sexual risk behavior, with some studies demonstrating an independent association between use of certain club drugs and HIV infection. The direct influence of club drugs on progression of HIV disease remains to be determined; however, club drugs may interact with certain retroviral medications and have been associated with decreased adherence to medication. Clinicians should ask all patients about patterns of club drug use, counsel patients about the risks associated with club drug use, and refer patients to appropriate behavioral treatment programs for substance use when clinically indicated.