Biological Impacts of Fluorination: Pharmaceuticals Based on Natural Products

Biological Impacts of Fluorination: Pharmaceuticals Based on Natural Products
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DOI：
10.1016/b978-0-444-53086-8.00013-8
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发表时间：
2008-01-01
期刊：
FLUORINE AND HEALTH: MOLECULAR IMAGING, BIOMEDICAL MATERIALS AND PHARMACEUTICALS
影响因子：
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通讯作者：
Bonnet-Delpon, Daniele
Bonnet-Delpon, Daniele
中科院分区：
其他
文献类型：
--
作者：
Begue, Jean-Pierre;Bonnet-Delpon, Daniele

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本章专门介绍了过去十年来天然产物氟化类似物的最新进展，这些天然产物被开发为药物，现已上市或正在开发（注册或临床开发）。这些主要涉及氟取代的核苷、生物碱、大环内酯、类固醇、氨基酸和甘草素。
This present chapter is devoted to the recent advances, for the last decade, in fluorinated analogues of natural products developed as pharmaceuticals and now marketed or in development (registered or in clinical development). These mainly concern fluorine-substituted nucleosides, alkaloids, macrolides, steroids, amino acids and prostaglandins.